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Letrozole comes in tablet form and is taken by mouth once dailyLetrozole can be taken with or without foodIf you miss a dosetake it as soon as you rememberIf it is almost time for your next doseskip the missed doseDo not take two doses at the same timeDo not stop taking letrozole without talking to your healthcare team.

The most serious side effects seen with FEMARA are bone effectsfracturesdecreased bone density and osteoporosisand increases in cholesterolOther common side effects seen with FEMARA include joint painnauseaweight decreasevaginal irritationand pain in the extremitiesOther important less commonly reported side effects include blood clotsother cancersstrokeheart attack and endometrial cancer.

2.5mg once dailyAdjuvant or extended adjuvant therapydiscontinue at tumor relapsesee full labelingAdvanced breast cancercontinue until tumor progression is evidentSevere hepatic impairment or cirrhosis2.5mg every other day.

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